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RESEARCH UPDATE
   


St. Nicholas Home > Research Update

Research

Also In Global Health News: Bird Flu In Bangladesh; Women's Health In Kenya; Drug-Resistant Malaria In Cambodia; Over-Diagnosis Of Malaria In Children

USAID Program To Prevent Spread Of Bird Flu In Bangladesh Expands All Headline News reports on a USAID-funded initiative to prevent the spread of bird flu in Bangladesh...

http://mnt.to/f/3FR4

Intercell Reports Phase II Study Results Of Its Vaccine Enhancement Patch For Pandemic Influenza

Intercell AG (VSE: ICLL) announced the results of a Phase II clinical trial of its investigational Vaccine Enhancement Patch (VEP) system for avian H5N1 influenza. In this development program, Intercell is working under a contract with the U.S...

http://mnt.to/f/3FLS

Emerging Pathogens Project

The Field Museum and the University of Chicago have announced the establishment of the Emerging Pathogens Project, a unique research program to study the evolution of species-switching parasites or pathogens that result in diseases such as bird flu, malaria, and AIDS. Many diseases have a long infection history in animals...

http://mnt.to/f/3Bzn


No Safe Level First Study To Show Teenage Binge Drinkers Harm Abilities In Later Life

Academics at Northumbria University have demonstrated a link between teenage binge drinking and damage to prospective memory. Prospective memory is an important aspect of day-to-day memory function and is defined as the cognitive ability to remember to carry out an activity at some future point in time...

http://mnt.to/f/3GPc

2 Programmes Focus On Addiction Awareness And Control

Funded by the Economic and Social Research Council (ESRC) the study designed the two programmes and examined their effectiveness in helping excessive drinkers reduce their drinking. The AACTP and LEAP programmes address the challenges faced by excessive drinkers, including a preoccupation with drinking made worse by alcohol-related stimuli around them...

http://mnt.to/f/3GNs

Drinkaware Response To Plans By The Government To Crack Down On Binge Drinking Hotspots, UK

Responding to the plan by the Government to crack down on binge drinking hotspots and give communities more influence over licensing applications, Chris Sorek, Chief Executive of alcohol awareness charity Drinkaware, says: "Alcohol misuse costs society £25 billion a year* and it is imperative our culture's binge drinking problem is tackled head on...

http://mnt.to/f/3GLt


Therapies For Heart Disease And Cancer May Benefit From Snake Venom Studies

Researchers seeking to learn more about stroke by studying how the body responds to toxins in snake venom are releasing new findings that they hope will aid in the development of therapies for heart disease and, surprisingly, cancer...

http://mnt.to/f/3GNF

Swimmers Make A Splash For A Good Cause

More than 200 swimmers took to the shores of Lake Michigan for the annual Swim Across America (SAA) fundraiser earlier this month. The event raised money for cancer research, prevention and treatment at Loyola University Health System's Cardinal Bernardin Cancer Center (CBCC)...

http://mnt.to/f/3GMb

NICE Gives Green Light To MabThera(R) (Rituximab) For Wider Use In Patients With Most Common Chronic Leukaemia

The National Institute for Health and Clinical Excellence (NICE) extended its recommendation for the use of targeted antibody MabThera® (rituximab) to include people with relapsed and difficult-to-treat (refractory) chronic lymphocytic leukaemia (CLL) except where patients have received the full therapeutic dose of MabThera in the first line setting or are refractory to fludarabine...

http://mnt.to/f/3GMF


Today's Opinions: Haiti's Lesson For The U.S.; Ending 'Pay For Delay;' Getting The CLASS Act Off The Ground

In Haiti, A Lesson For U.S. Health Care The New York Times In February, a month after Haiti's earthquake, I went down to Port-au-Prince as part of a team that was helping to reactivate cardiac care in the city's public hospital. For several months since, I have observed how the earthquake and its aftermath profoundly changed Haiti's health care system...

http://mnt.to/f/3GMV

Also In Global Health News: Child Marriages; USAID In Afghanistan; Respiratory Diseases In El Salvador; Food Security Improving In Zimbabwe

Epoch Times Examines Child Marriage Hearing An Epoch Times article discusses a recent congressional hearing held by the Tom Lantos Human Rights Commission on child marriage...

http://mnt.to/f/3GN6

Health Experts Express Concern About U.S. Funding For International AIDS Treatment

Health experts at last week's International AIDS Conference in Vienna expressed anger and concern about future U.S. funding for HIV treatment in developing nations and the knowledge that due to funding constraints, some African nations already are turning away patients who need treatment, the Washington Post reports. According to the Post, current funding levels barely cover the 5...

http://mnt.to/f/3GMt


Usability Testing of an Online Self-management Program for Adolescents With Juvenile Idiopathic Arthritis

Background: A new bilingual (English and French) Internet-based self-management program, Teens Taking Charge: Managing Arthritis Online, for adolescents with arthritis and their parents was developed following a needs assessment. Objective: This study explored the usability (user performance and satisfaction) of the self-management program for youth with juvenile idiopathic arthritis (JIA) and their parents to refine the health portal prototype. Methods: A qualitative study design with semi-structured, audio taped interviews and observation by a trained observer was undertaken with two iterative cycles to determine the usability (ease of use, efficiency, errors, and user satisfaction) of the user interface and content areas of the intervention. A purposive sample of English-speaking (n = 11; mean age = 15.4, standard deviation [SD] 1.7) and French-speaking (n = 8; mean age = 16.0, SD 1.2) adolescents with JIA and one of their respective parents/caregivers were recruited from 2 Canadian tertiary care centers. Descriptive statistics and simple content analyses were used to organize data into categories that reflected the emerging usability themes. Results: All of the participants had access to a computer/Internet at home; however, adolescents were more comfortable using the computer/Internet than their parents. Adolescents and parents provided similar as well as differing suggestions on how the website user-interface could be improved in terms of its usability (navigation, presentation and control usage errors; format and layout; as well as areas for further content development). There were no major differences in usability issues between English- and French-speaking participants. Minor changes to the website user interface were made and tested in a second cycle of participants. No further usability problems were identified in the second iterative cycle of testing. Teens and parents responded positively to the appearance and theme of the website (ie, promoting self-management) and felt that it was easy to navigate, use, and understand. Participants felt that the content was appropriate and geared to meet the unique needs of adolescents with JIA and their parents as well as English- and French-speaking families. Many participants responded that the interactive features (discussion board, stories of hope, and video clips of youth with JIA) made them feel supported and “not alone” in their illness. Conclusions: We describe the usability testing of a self-management health portal designed for English- and French-speaking youth with arthritis and their parents, which uncovered several usability issues. Usability testing is a crucial step in the development of self-management health portals to ensure that the various end users (youth and parents) have the ability to access, understand, and use health-related information and services that are delivered via the Internet and that they are delivered in an efficient, effective, satisfying, and culturally competent manner.

http://www.jmir.org/2010/3/e30

Information-Seeking at a Caregiving Website: A Qualitative Analysis

Background: The Internet is widely used for health information, yet little is known about the online activity of family caregivers of elders, a rapidly growing group. In order to better understand the online information-seeking activity of “e-caregivers” and other visitors at a caregiving website, we undertook a qualitative analysis of survey data from a website marketed as a comprehensive resource for adults caring for aging parents. Objective: The objectives were to better understand what types of information are sought by those visiting a website focused on elder-care issues and to identify overarching themes that might inform future development of Internet resources related to caregiving and aging. Methods: From March 2008 to MarcFrom March 2008 to March 2009, a 5-question pop-up survey was offered 9662 times and completed 2161 times. For 1838 respondents, included was a free text answer to the question "What were you looking for?” and 1467 offered relevant and detailed responses. The survey also asked about satisfaction with the site, gender of the respondent, and relationship to the individual being cared for. Content analysis was used to develop a coding dictionary, to code responses into information-seeking categories, and to identify overarching themes. Results: Of the respondents (76% of whom were female), 50% indicated they were caring for parents, 17% for themselves only, and 31% for others. Over half (57%) reported finding what they were looking for, and 46% stated they were extremely likely to recommend the website. Frequently mentioned information-seeking categories included “health information,” “practical caregiving,” and “support.” Respondents also requested information related to housing, legal, insurance, and financial issues. Many responses referred to multiple comorbid conditions and complex caregiving situations. Overarching themes included (1) a desire for assistance with a wide range of practical skills and information and (2) help interpreting symptoms and behavior, such as knowing what life impacts to expect over the course of a health condition or treatment. Conclusions: Visitors to a website targeting adults caring for aging parents reported seeking both general information on caregiving and specific assistance with the complex custodial, medical, emotional, and financial aspects of caregiving. Visitors requested both information to build caregiving skills as well as assistance in interpreting and knowing what to expect from symptoms, health conditions, and changes in behavior and relationships. Many desired communication with and support from other caregivers. Health care providers and eHealth developers should expect that many caregivers of elders are using the Internet as a resource. Further research and development is needed to fully realize the Internet’s potential for education and support of caregivers.

http://www.jmir.org/2010/3/e31

Associations of Internet Website Use With Weight Change in a Long-term Weight Loss Maintenance Program

Background: The Weight Loss Maintenance Trial (WLM) compared two long-term weight-maintenance interventions, a personal contact arm and an Internet arm, with a no-treatment control after an initial six-month Phase I weight loss program. The Internet arm focused on use of an interactive website for support of long-term weight maintenance. There is limited information about patterns of website use and specific components of an interactive website that might help promote maintenance of weight loss. Objective: This paper presents a secondary analysis of the subset of participants in the Internet arm and focuses on website use patterns and features associated with long-term weight maintenance. Methods: Adults at risk for cardiovascular disease (CVD) who lost at least 4 kilograms in an initial 20-week group-based, behavioral weight-loss program were trained to use an interactive website for weight loss maintenance. Of the 348 participants, 37% were male and 38% were African American. Mean weight loss was 8.6 kilograms. Participants were encouraged to log in at least weekly and enter a current weight for the 30-month study period. The website contained features that encouraged setting short-term goals, creating action plans, and reinforcing self-management habits. The website also included motivational modules, daily tips, and tailored messages. Based on log-in and weight-entry frequency, we divided participants into three website use categories: consistent, some, and minimal. Results: Participants in the consistent user group (n = 212) were more likely to be older (P = .002), other than African American (P = .02), and more educated (P = .01). While there was no significant difference between website use categories in the amount of Phase I change in body weight (P = .45) or income (P = .78), minimal website users (n = 75) were significantly more likely to have attended fewer Phase I sessions (P = .001) and had a higher initial body mass index (BMI) (P < .001). After adjusting for baseline characteristics including initial BMI, variables most associated with less weight regain included: number of log-ins (P = .001), minutes on the website (P < .001), number of weight entries (P = .002), number of exercise entries (P < .001), and sessions with additional use of website features after weight entry (P = .002). Conclusion: Participants defined as consistent website users of an interactive behavioral website designed to promote maintenance of weight loss were more successful at maintaining long-term weight loss. Trial Registration: NCT00054925; http://clinicaltrials.gov/ct2/show/NCT00054925 (Archived by WebCite at http://www.webcitation.org/5rC7523ue)

http://www.jmir.org/2010/3/e29


Thirty Million Women Will Gain From Health Reform Law, Including About 15 Million Uninsured

Approximately thirty million American women will gain from the new health reform law over the next ten years, according to a new report from The Commonwealth Fund, a private foundation based in New York. The authors state that the law will stabilize women's growing exposure to ever-increasing health costs, and even reverse it, by subsidizing health insurance for approximately 15 million women who currently have to no health insurance cover, while at the same time strengthening existing coverage for another 14.5 million women deemed underinsured...


http://feedproxy.google.com/~r/mnt/healthnews/~3/9tdXbltz1l8/3GPx

Seven Influenza Vaccines For Coming Season Approved By FDA

The US FDA (Food and Drug Administration) has approved vaccines for the 2010-2011 USA influenza season, protecting against three strains of influenza, including the H1N1 virus which caused the 2009 pandemic. In 2009, because the H1N1 virus appeared after seasonal vaccine production commenced, two separate vaccines were required to protect against the seasonal flu and the 2009 H1N1 pandemic flu virus. The FDA says that only one vaccine is needed for this year...


http://feedproxy.google.com/~r/mnt/healthnews/~3/AcRtLwudLY4/3GPv

Why Are UK Stroke Patients Still Not Getting Prompt Treatment?

The Lancet this week featured an Editorial discussing a recent report from the UK Vascular Society and Royal College of Physicians showing that the waiting time for vascular surgery after symptoms of stroke or transient ischemic attack is far too long. Guidelines set by the UK National Institute for Health and Clinical Excellence (NICE) suggest no more than a 14 day wait between symptoms and operation. The 2007 National Stroke Strategy is targeting for there to be a 48 hour wait by 2017...


http://feedproxy.google.com/~r/mnt/healthnews/~3/3QYZ3Dd4Ihs/3GPs


FDA Approves Embryonic Stem Cell-Based Therapy For Patients With Acute Spinal Cord Injury

The US FDA (Food and Drug Administration) has lifted a clinical hold on Geron's Investigational New Drug (IND) application - the Phase I clinical trial of GRNOPC1 in patients with acute spinal cord injury may now go ahead. GRNOPC1 is the first ever clinical trial of a human embryonic stem cell based therapy in humans...

http://mnt.to/f/3GPt

Biogen Idec And Swedish Orphan Biovitrum Present Data On Long-Lasting Hemophilia B Therapy At The World Federation Of Hemophilia Congress

Biogen Idec (NASDAQ: BIIB) and Swedish Orphan Biovitrum AB (STO: SOBI) announced results from a Phase 1/2a open-label, dose-escalation, safety and pharmacokinetic study of the companies' long-lasting, fully-recombinant factor IX Fc fusion protein (rFIXFc) in hemophilia B patients...

http://mnt.to/f/3GPn

Orexigen® Therapeutics Announces Publication Of COR-I Phase 3 Study Of Contrave In Lancet

Orexigen® Therapeutics, Inc. (Nasdaq: OREX) announced that results from its COR-I trial of Contrave® were published online in the journal Lancet. COR-I was the largest of the four, 56-week, Phase 3 trials supporting the New Drug Application for Contrave, currently under review by the U.S. Food and Drug Administration...

http://mnt.to/f/3GLZ


The Mystery Of Healthy Fat People

Why some obese people go on to become diabetic while others do not. It is common to find obese people even morbidly obese people who are healthier than their condition would normally allow...

http://mnt.to/f/3GPd

Rising Obesity In Pregnancy Causes Concern For Gestational Diabetes

A NHS watchdog revealed concerns about the rising level of obesity among pregnant women yesterday in order to raise awareness of the associated complications, which includes gestational diabetes...

http://mnt.to/f/3GNg

Just Drop It: The One-Size-Fits-All Approach To Blood Sugar Control, That Is

Aggressive blood sugar control does not improve survival in diabetic patients with kidney failure, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The results suggest that physicians should individualize blood sugar targets for these patients and not rely on recommendations based on studies in the general population...

http://mnt.to/f/3GM8
 
 
   
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